{
  "clinical_comparison": {
    "title": "Urinary recovery after two broccoli sprout beverages",
    "metric": "Mean urinary excretion of sulforaphane and metabolites, approximately 12-hour collection; percent of dose",
    "data": [
      {
        "label": "Glucoraphanin-rich beverage",
        "value": 5
      },
      {
        "label": "Sulforaphane-rich beverage",
        "value": 70
      }
    ],
    "source": "https://doi.org/10.1158/1940-6207.CAPR-10-0296",
    "authors": "Egner et al.",
    "year": 2011,
    "participants": 50,
    "type": "Published human crossover trial; redrawn summary means, not Yisheng Maolian testing",
    "limits": "Different study preparations; descriptive comparison only. No error bars or individual values reconstructed. Not a prediction for a commercial extract. Different administered input amounts: 800 µmol GR and 150 µmol SF; these are experimental inputs, not recommended doses or an equal-powder-mass comparison.",
    "unit": "% of the respective administered study dose recovered in urine",
    "study_inputs": [
      {
        "label": "Glucoraphanin-rich beverage",
        "administered_compound": "glucoraphanin",
        "amount_umol": 800
      },
      {
        "label": "Sulforaphane-rich beverage",
        "administered_compound": "sulforaphane",
        "amount_umol": 150
      }
    ],
    "protocol": "50 randomized participants; 5-day run-in, 7-day intervention, 5-day washout, 7-day crossover intervention. Main urinary endpoint approximately 0–12 hours after dosing.",
    "protocol_source": "https://pubmed.ncbi.nlm.nih.gov/21372038/",
    "checked_on": "2026-10-26"
  },
  "assay_calculation": {
    "type": "Illustrative calculation, not measured product data or a recommended dose",
    "input_mass_mg": 500,
    "assays_percent": [
      1,
      5,
      10,
      20
    ],
    "marker_mass_mg": [
      5,
      25,
      50,
      100
    ],
    "formula": "marker mass (mg) = ingredient mass (mg) × assay (%) / 100"
  },
  "nist_green_tea": {
    "title": "Selected catechins in NIST SRM 3255",
    "source": "https://tsapps.nist.gov/srmext/certificates/3255.pdf",
    "source_location": "Table 1, PDF page 4",
    "certificate_issue_date": "2018-02-09",
    "checked_on": "2026-10-26",
    "unit": "mg/g dry mass",
    "uncertainty": "Published expanded uncertainty at approximately 95% confidence; not reconstructed standard deviations",
    "data": [
      {
        "label": "EC",
        "analyte": "epicatechin",
        "value": 47.3,
        "expanded_uncertainty": 6.7
      },
      {
        "label": "ECG",
        "analyte": "epicatechin gallate",
        "value": 100.3,
        "expanded_uncertainty": 7.8
      },
      {
        "label": "EGC",
        "analyte": "epigallocatechin",
        "value": 81.8,
        "expanded_uncertainty": 6.5
      },
      {
        "label": "EGCG",
        "analyte": "epigallocatechin gallate",
        "value": 422,
        "expanded_uncertainty": 19
      }
    ],
    "limits": "Selected constituents in an external analytical reference material, not complete composition, a commercial specification or Yisheng Maolian product data.",
    "use_boundary": "Analytical research reference material; not for human consumption, as stated in its certificate."
  },
  "patent_resveratrol": {
    "title": "Selected purity stages reported in US11136283B2 Example 2",
    "source": "https://patents.google.com/patent/US11136283B2/en",
    "source_location": "Example 2, adjacent to Table 4 / Figure 3",
    "checked_on": "2026-10-26",
    "unit": "g resveratrol per 100 g dry material",
    "data": [
      {
        "label": "Crude",
        "value": 70
      },
      {
        "label": "Semi-crude",
        "value": 97.6
      },
      {
        "label": "Final",
        "value": 98.7
      }
    ],
    "overall_downstream_yield_percent": 73,
    "limits": "Patent-reported fermentation-route example, not independent replication, not our manufacturing route or lot data. Yield and purity use different denominators. No uncertainty is reported.",
    "final_step_recovery_percent": 97.6,
    "final_step_recovery_basis": "Resveratrol in the semi-crude material entering the final purification operation; distinct from semi-crude purity of 97.6 g per 100 g dry sample."
  }
}
